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How is DMT produced?: The link between DMT and spiritualism has been around a long time. A common theory about why DMT is in the body is that we release a large dose of it when we die. When people come back from a near death experience, and report seeing a white light or divine beings, some say this is the result of a release of DMT, which gives the brain a final, all-encompassing hallucination. In the Amazon, ayahuasca is a combination of DMT and a plant that contains an inhibitor of the enzyme that normally breaks down DMT. The result is a DMT drink that has been used for over 500 years. When taken orally, DMT can cause nausea, vomiting, and diarrhea. Depending on the individual user, the DMT experience can range from intensely exciting to overwhelmingly frightening. The experience can be so powerful that users may have difficulty processing and integrating the "trip" into their real life. Mental side effects may linger for many days or weeks after ingestion of the drug. DMT is structurally related to the neurotransmitter serotonin and, because of this, a condition called serotonin syndrome is a potentially lethal health risk associated with its use. Individuals taking antidepressants are at highest risk for this complication. N,N-Dimethyltryptamine has a similar chemical root structure to an anti-migraine drug called sumatriptan. DMT is a white crystalline powder that is derived from certain plants found in Mexico, South America, and parts of Asia, such as Psychotria viridis and Banisteriopsis caapi. It is typically consumed in the following ways: vaporized or smoked in a pipe consumed orally in brews like ayahuasca, snorted or injected on rare occasions. The chemical root structure of DMT is similar to the anti-migraine drug sumatriptan, and it acts as a non-selective agonist at most or all of the serotonin receptors, particularly at the serotonin 5-ht2a receptor. Serotonin is a neurotransmitter that has a large effect on the majority of our brain cells.